Dissecting the Immune Response Elicited by WbALT-2, ALT MAP in Clinical Populations and Mouse Model: A Prophylactic Measure Against Lymphatic Filariasis.
Identifieur interne : 001E91 ( Main/Exploration ); précédent : 001E90; suivant : 001E92Dissecting the Immune Response Elicited by WbALT-2, ALT MAP in Clinical Populations and Mouse Model: A Prophylactic Measure Against Lymphatic Filariasis.
Auteurs : Aparnaa Ramanathan [Inde] ; Christiana Immanuel [Inde] ; Donthamsetty Nageswara Rao [Inde] ; Perumal Kaliraj [Inde]Source :
- Lymphatic research and biology [ 1557-8585 ] ; 2015.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antihelminthe (immunologie), Antigènes d'helminthe (), Antigènes d'helminthe (immunologie), Brugia malayi (immunologie), Filariose lymphatique (), Filariose lymphatique (immunologie), Filariose lymphatique (parasitologie), Humains, Immunité cellulaire, Immunoglobuline G (immunologie), Inde, Larve, Lymphocytes T (immunologie), Lymphocytes T (métabolisme), Modèles animaux de maladie humaine, Protéines recombinantes (), Protéines recombinantes (immunologie), Souris, Séquence d'acides aminés, Épitopes (), Épitopes (immunologie).
- MESH :
- immunologie : Anticorps antihelminthe, Antigènes d'helminthe, Brugia malayi, Filariose lymphatique, Immunoglobuline G, Lymphocytes T, Protéines recombinantes, Épitopes.
- métabolisme : Lymphocytes T.
- parasitologie : Filariose lymphatique.
- Animaux, Antigènes d'helminthe, Filariose lymphatique, Humains, Immunité cellulaire, Inde, Larve, Modèles animaux de maladie humaine, Protéines recombinantes, Souris, Séquence d'acides aminés, Épitopes.
- Wicri :
- geographic : Inde.
English descriptors
- KwdEn :
- Amino Acid Sequence, Animals, Antibodies, Helminth (immunology), Antigens, Helminth (chemistry), Antigens, Helminth (immunology), Brugia malayi (immunology), Disease Models, Animal, Elephantiasis, Filarial (immunology), Elephantiasis, Filarial (parasitology), Elephantiasis, Filarial (prevention & control), Epitopes (chemistry), Epitopes (immunology), Humans, Immunity, Cellular, Immunoglobulin G (immunology), India, Larva, Mice, Recombinant Proteins (chemistry), Recombinant Proteins (immunology), T-Lymphocytes (immunology), T-Lymphocytes (metabolism).
- MESH :
- chemical , chemistry : Antigens, Helminth, Epitopes, Recombinant Proteins.
- chemical , immunology : Antibodies, Helminth, Antigens, Helminth, Epitopes, Immunoglobulin G, Recombinant Proteins.
- geographic : India.
- immunology : Brugia malayi, Elephantiasis, Filarial, T-Lymphocytes.
- metabolism : T-Lymphocytes.
- parasitology : Elephantiasis, Filarial.
- prevention & control : Elephantiasis, Filarial.
- Amino Acid Sequence, Animals, Disease Models, Animal, Humans, Immunity, Cellular, Larva, Mice.
Abstract
Abundant Larval Transcript (ALT) is one of the major groups of immune-dominant proteins produced by filarial worms during their larval stage. The major B-cell and T-cell epitopic domains of the ALT-2 antigen were mapped to develop a multiple antigenic peptide (MAP) prophylactic antigen against lymphatic filariasis.
DOI: 10.1089/lrb.2014.0034
PubMed: 26091407
Affiliations:
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first="Christiana" last="Immanuel">Christiana Immanuel</name><affiliation wicri:level="1"><nlm:affiliation>1 Centre For Biotechnology, Anna University , Chennai, India .</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>1 Centre For Biotechnology, Anna University , Chennai</wicri:regionArea><wicri:noRegion>Chennai</wicri:noRegion></affiliation></author><author><name sortKey="Rao, Donthamsetty Nageswara" sort="Rao, Donthamsetty Nageswara" uniqKey="Rao D" first="Donthamsetty Nageswara" last="Rao">Donthamsetty Nageswara Rao</name><affiliation wicri:level="1"><nlm:affiliation>2 Department of Biochemistry, All India Institute of Medical Sciences , New Delhi, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>2 Department of Biochemistry, All India Institute of Medical Sciences , New Delhi</wicri:regionArea><wicri:noRegion>New Delhi</wicri:noRegion></affiliation></author><author><name sortKey="Kaliraj, Perumal" sort="Kaliraj, Perumal" 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Cellular</term><term>Larva</term><term>Mice</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Antigènes d'helminthe</term><term>Filariose lymphatique</term><term>Humains</term><term>Immunité cellulaire</term><term>Inde</term><term>Larve</term><term>Modèles animaux de maladie humaine</term><term>Protéines recombinantes</term><term>Souris</term><term>Séquence d'acides aminés</term><term>Épitopes</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Inde</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abundant Larval Transcript (ALT) is one of the major groups of immune-dominant proteins produced by filarial worms during their larval stage. The major B-cell and T-cell epitopic domains of the ALT-2 antigen were mapped to develop a multiple antigenic peptide (MAP) prophylactic antigen against lymphatic filariasis.</div></front></TEI><affiliations><list><country><li>Inde</li></country></list><tree><country name="Inde"><noRegion><name sortKey="Ramanathan, Aparnaa" sort="Ramanathan, Aparnaa" uniqKey="Ramanathan A" first="Aparnaa" last="Ramanathan">Aparnaa Ramanathan</name></noRegion><name sortKey="Immanuel, Christiana" sort="Immanuel, Christiana" uniqKey="Immanuel C" first="Christiana" last="Immanuel">Christiana Immanuel</name><name sortKey="Kaliraj, Perumal" sort="Kaliraj, Perumal" uniqKey="Kaliraj P" first="Perumal" last="Kaliraj">Perumal Kaliraj</name><name sortKey="Rao, Donthamsetty Nageswara" sort="Rao, Donthamsetty Nageswara" uniqKey="Rao D" first="Donthamsetty Nageswara" last="Rao">Donthamsetty Nageswara Rao</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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